In his Chronicle, he illustrated the most important world events, he also painted over a hundred personalities, writers – Zbigniew Herbert, George Wells, Graham Greene, politicians – Harold Macmillan, Winston Churchill, and many other famous individuals. The Chronicle was his medium for presenting his art and thoughts about people, politics, and events. Extraordinarily energetic and slightly satirical, his graphic style perfectly suited both landscape frames and precisely-modulated details. The album won an enormous popularity as an artistic account of nearly thirty years of human history. The Chronicle was made up of three thousand drawings. It was exhibited in New York, Moscow, Köln, Hamburg, and Tel Aviv, and also published in parts in the United States, Poland, Italy, Denmark, and Switzerland. Topolski thus described his work:
I keep drawing and my drawings immediately enter my chronicle, which travels the world with me, and in consequence, covers nearly the entire planet. And let’s say these drawings are a material that I collect for my paintings. Since the material is enormous and I’m captivated by size, so I paint many enormous wall paintings.
He was a renowned portrait artist. He used tangled dynamic lines to bluntly portray his models, at times in an almost caricatural manner. Drawing was his expression of choice. He usually worked with pencils, crayons, and ink. He drew using a thick entanglement of lines, which made up exquisitely characterised personalities and scenes. He always drew his works on the run, quickly and on-site and he never redrew them. Thus, they can be treated as quick, seemingly chaotic, yet always clever and authentic notes.
Between 1961 and 1962, Topolski was commissioned by the University of Texas in Austin to paint the portraits of twenty living distinguished British poets and writers: W. H. Auden, John Betjeman, Cyril Connolly, T. S. Eliot, William Empson, E. M. Forster, Graham Greene, Aldous Huxley, C. Day Lewis, John Osborne, J. B. Priestley, Herbert Read, Bertrand Russell, Stephen Spender, Edith Sitwell, Evelyn Waugh, and John Whiting.