From 2004 to 2006 she worked as a journalist in the Łódź edition of Gazeta Wyborcza. In 2006, she was appointed director of the 2006 Łódź Biennale (the second edition of the International Biennial of Art), and a year later she launched and became head of the first festival of design and architecture in Poland – Łódź Design. She also lectured on art history and marketing in the culture sector at the Academy of Fine Arts in Łódź (2007-10). She has authored many critical texts published in specialized magazines about art and culture: Obieg, Arteon and Kresy.
From 2008, she was the deputy director of the largest institution dedicated to modern art in Poland – the Museum of Art in Łódź. In 2014, she became the director of the Centre for Contemporary Art in Warsaw.
(...) I could say that I am a Varsovian from Łódź. My family’s connection to the capital dates back to the eighteenth century. My grandparents lived and raised their children in the Żoliborz district until the end of the uprising. Soon after, they have moved to Łódź, where my mother was born. The way I was brought up made me emotionally linked to the city. (...) Thus, I could say that I'm not moving to, but returning to Warsaw
– declared Ludwisiak in an interview conducted by Anna Szawiel for Gazeta Wyborcza.
She has also curated a number of exhibitions, including C.D.N./T.B.C as part of the Dialogue of Four Cultures Festival in 2008, and Korespondencje. Sztuka Nowoczesna i Uniwersalizm/ Correspondences: Modern Art and Universalism at the Museum of Art in Łódź (in collaboration with Jarosław Lubiak).
As director of the Centre for Contemporary Art she plans to introduce some changes in the institution. In an interview with Małgorzata Piwowar for Rzeczpospolita she stated:
One of our priorities must be to introduce the CCA onto the international art circuit. As a matter of fact, the changes we have in mind come down to reflecting on and referring anew to the best traditions and the times when the CCA shaped discourse on art, and offered interpretations not only of art, but also of contemporary culture as a whole. It is also important to me to bring up the way Wojciech Krukowski thought of the CCA as a space where there is room for visual arts and performing arts in general: theatre, dance and sound. One of the main points of my proposal for the CCA's programme is to create a space for confrontation with globalization, which is our current reality. And this, I hope, will make us different from other Polish cultural institutions.